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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC5
All Species:
34.85
Human Site:
T481
Identified Species:
63.89
UniProt:
Q13769
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13769
NP_001002877.1
683
78508
T481
T
T
M
K
L
L
K
T
R
V
Q
S
R
L
A
Chimpanzee
Pan troglodytes
XP_515059
683
78517
T481
T
T
M
K
L
L
K
T
R
V
Q
S
R
L
A
Rhesus Macaque
Macaca mulatta
XP_001106294
689
79038
T487
T
T
M
K
L
L
K
T
R
V
Q
S
R
L
A
Dog
Lupus familis
XP_534728
683
78595
T481
T
T
M
K
L
L
K
T
R
V
Q
S
R
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKT7
683
78667
T481
T
T
M
K
L
L
K
T
R
V
Q
S
R
L
A
Rat
Rattus norvegicus
Q68FX7
682
78642
T480
T
T
M
K
L
L
K
T
R
V
Q
S
R
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517072
363
40527
H170
L
Q
A
R
L
A
L
H
K
Q
F
S
S
L
E
Chicken
Gallus gallus
Q5ZJK1
698
80563
T496
M
T
M
K
L
L
R
T
R
L
Q
S
R
L
A
Frog
Xenopus laevis
Q7ZXA8
678
77744
T476
K
T
I
K
L
L
K
T
R
L
L
S
R
L
S
Zebra Danio
Brachydanio rerio
Q6NY52
684
77815
G481
K
S
M
K
L
L
R
G
R
L
Q
S
R
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1F4
616
70871
W423
I
A
R
R
L
N
S
W
Q
R
L
S
Q
Q
I
Honey Bee
Apis mellifera
XP_396039
657
75378
L464
P
D
A
R
E
Q
K
L
T
S
C
E
K
T
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798236
699
79519
S489
S
T
V
K
A
L
K
S
R
V
K
A
R
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.5
98
N.A.
96.1
96.1
N.A.
45.2
83.2
76.5
68.4
N.A.
25.7
37
N.A.
46.2
Protein Similarity:
100
100
96.3
99.1
N.A.
97.9
98.3
N.A.
49.7
90.9
87.1
83
N.A.
45.3
56.2
N.A.
65.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
80
66.6
66.6
N.A.
13.3
6.6
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
93.3
86.6
86.6
N.A.
33.3
20
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
8
8
0
0
0
0
0
8
0
0
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
16
0
0
77
0
0
70
0
8
0
8
0
8
0
0
% K
% Leu:
8
0
0
0
85
77
8
8
0
24
16
0
0
85
0
% L
% Met:
8
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
8
8
62
0
8
8
8
% Q
% Arg:
0
0
8
24
0
0
16
0
77
8
0
0
77
0
0
% R
% Ser:
8
8
0
0
0
0
8
8
0
8
0
85
8
0
8
% S
% Thr:
47
70
0
0
0
0
0
62
8
0
0
0
0
8
8
% T
% Val:
0
0
8
0
0
0
0
0
0
54
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _